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Diabetes

May 2007

Diabetes is a major risk for cardiovascular disease

  • High blood glucose is a greater risk for ischemic heart disease (IHD) and stroke than smoking.1
  • People with diabetes have a higher prevalence of CVD risk factors and these are more harmful in the presence of diabetes than in people without diabetes.2
  • For each CVD risk factor present, the risk of CVD death is about 3 times greater in people with diabetes compared to people without diabetes.2
  • People with diabetes are 2 to 4 times more likely to develop CVD disease than people without diabetes, making it the most common complication of diabetes.2
  • Women with diabetes lose the pre-menopausal protective effect of estrogen so that their CVD risk is the same as most men’s.2
  • Young adults with diabetes have rates of coronary heart disease (CHD) 12–40 times higher than those in people without diabetes.3
  • Strokes happen twice as often in people with diabetes and hypertension compared to people with hypertension alone.2

Diabetes and CVD death: the statistics

  • CVD accounts for 50% of all fatalities in people with diabetes.2
  • After a coronary event, people with diabetes have a 1.5 to 2 times higher death rate than those without.2
  • 84% of CVD diabetes-related deaths occur in low and middle income countries.1
  • South Asia accounts for 37% of worldwide diabetes-related IHD deaths 30% of worldwide stroke deaths.1
  • The countries of the former Soviet Union have the largest CVD diabetes-related mortality rate of any region.1

Epidemiology of diabetes

  • There are 246 million people in the world with diabetes.4
  • Diabetes is rare where traditional lifestyles have persisted but where communities have undergone westernization and urbanization the prevalence of diabetes ranges from 14 to 20%.4
  • India and China are at the forefront of the diabetes epidemic.4
  • The Eastern Mediterranean and Middle East have the highest prevalence rates (9.2%) of diabetes followed by North America (8.4%).5

The future of diabetes

  • By 2025 it is estimate that 380 million people will have diabetes, the increase driven by the rise in overweight and obesity.4
  • In 2025, 80% of all cases of diabetes will be in low and middle income countries.5

Cost of diabetes

  • In 2007, the world will spend at least €172.58 billion to treat and prevent diabetes and its complications. By 2025, this will be at least €225 billion.2
  • Managing diabetes uses up about 10% of national healthcare budgets in many countries; about half is spent on the complications of diabetes of which CVD is the most significant drain on resources.2
  • The CVD complications of diabetes could overwhelm developing countries that are still struggling to manage communicable diseases.4


1 Danaei G, Lawes CMM, Vander Hoorn S, Murray CJL, Ezzati M. Global and regional mortality from ischaemic heart disease and stroke attributable to higher-than-optimum blood glucose concentration: comparative risk assessment. Lancet 2006; 368: 1651–59.

2 International Diabetes Federation. Diabetes and CVD Disease: A Time to Act. 2001. IDF. Brussels.

3 Booth GL, Kapral MK, Fung K, Tu JV. Relation between age and cardiovascular disease in men and women with diabetes compared with non-diabetic people: a population-based retrospective cohort study. Lancet. 2006;368(9529):29-36.

4 International Diabetes Federation. Diabetes Atlas, Third Edition. IDF, Brussels, 2007

5 United Nations Resolution 61/225: World Diabetes Day. 2007